There have been a few questions on the blog about the congenital form of Myotonic Dystrophy and whether this occurs in DM2 patients as well as in DM1 patients. Toba in Canada is the resident expert on DM2 and runs the yahoo groups DM2 but I did find this older article from 2006 on this subject and am posting it here.
Outcome and effect of pregnancy in myotonic dystrophy type 2
10.1212/01.wnl.0000198227.91131.1e Neurology February 28, 2006 vol. 66 no. 4 579-580
- S. Rudnik-Schöneborn, MD, et. al Address correspondence and reprint requests to Dr. Sabine Rudnik-Schöneborn, Institut für Humangenetik, RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany; e-mail: srudnik-schoeneborn@ukaachen.de
Abstract
The authors reviewed the obstetric histories of 42 women of 37 families with myotonic dystrophy type 2 (DM2). Nine women (21%) had the first symptoms during pregnancy and worsening in subsequent pregnancies. Of 96 pregnancies, 13% ended as early and 4% as late miscarriages. Preterm labor occurred in 50% of pregnancies resulting in 27% preterm deliveries in women with overt DM2 in pregnancy. There was no evidence of a congenital DM2.
Fight: Dave Anderson is calling for more resources
